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Capetrox

Capetrox

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Capetrox
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Capetrox

Category:
Composition: Capecitabine Tablets
Strength: 500 mg

Description:

Capetrox (Capecitabine Tablets 500 mg) is an oral chemotherapy drug used in the treatment of various solid tumors. It is a prodrug that is enzymatically converted in the body to 5-fluorouracil (5-FU), a cytotoxic agent that interferes with DNA synthesis in cancer cells, leading to their death. Its targeted conversion within tumor tissues helps maximize efficacy while minimizing systemic toxicity.
Capecitabine is converted to 5-FU preferentially within tumor cells. 5-FU inhibits the enzyme thymidylate synthase, disrupting DNA synthesis and repair. This selectively impacts rapidly dividing cancer cells, slowing or stopping tumor growth. 5 – FU inhibits the enzyme thymidylate synthase.

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Description

Dosage and Administration
  • Dosage may vary based on body surface area, cancer type, and combination regimen.
  • Should be taken within 30 minutes after a meal.
  • Tablets must be swallowed whole with water.
  • Hand-foot syndrome (palmar-plantar erythrodysesthesia)
  • Diarrhea
  • Nausea and vomiting
  • Fatigue
  • Abdominal pain
  • Loss of appetite
  • Mucositis
  • Mild skin reactions
  • Severe diarrhea and dehydration
  • Myelosuppression (anemia, neutropenia, thrombocytopenia)
  • Liver enzyme abnormalities
  • Use with caution in patients with liver or kidney impairment
  • Not recommended in pregnancy or breastfeeding; effective contraception is necessary during treatment
  • Monitor complete blood counts, liver and kidney function during therapy
  • Avoid drugs that interfere with blood clotting (e.g., warfarin) without doctor’s advice
  • Patients should be educated about early symptoms of hand-foot syndrome and diarrhea.